WHO: No Proven Link Between Paracetamol Use During Pregnancy and Autism

In Health & Wellness
September 29, 2025

The World Health Organization (WHO) has clarified that there is currently no conclusive scientific evidence linking the use of paracetamol (also known as acetaminophen) during pregnancy to autism spectrum disorder (ASD) in children. This statement comes amid recent claims by public figures suggesting a potential connection, which the WHO says is unproven and inconsistent with existing research.

During a press briefing in Geneva, WHO spokesperson Tarik Jašarević emphasized that while some studies have reported associations between prenatal paracetamol use and neurodevelopmental outcomes, these findings do not establish a causal relationship. He also reaffirmed the WHO’s position that vaccines do not cause autism, countering misinformation circulating in public discourse.

The clarification coincides with actions by the U.S. Food and Drug Administration (FDA), which has initiated updates to acetaminophen product labels to reflect concerns about possible links to conditions such as autism and attention-deficit/hyperactivity disorder (ADHD). However, the FDA maintains that paracetamol remains the safest option for pain and fever relief during pregnancy when used as recommended, stressing that benefits outweigh potential risks if taken appropriately.

European health authorities, including the European Medicines Agency (EMA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA), have also affirmed the safety of paracetamol for pregnant individuals. Experts advise that untreated pain or fever during pregnancy can pose significant risks to both the mother and the fetus, and that paracetamol should be used at the lowest effective dose for the shortest possible duration.

Medical professionals have criticized recent public claims linking paracetamol to autism as misleading and potentially harmful, noting that spreading unfounded concerns can create unnecessary anxiety among pregnant individuals. Health experts warn that fear of taking safe medications may prevent expectant mothers from seeking appropriate care, potentially endangering both maternal and fetal health.

While research into prenatal medication use continues, the current scientific consensus does not support a direct link between paracetamol use during pregnancy and autism. Pregnant individuals are encouraged to consult their healthcare providers for personalized guidance on medication, ensuring the health and safety of both mother and child.

IMAGE COURTESY OF NUFFIELD DEPARTMENT